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Antineoplastic Agents. 595. Structural Modifications of Betulin and the X-ray Crystal Structure of an Unusual Betulin Amine Dimer1
[Image: see text] The lupane-type triterpene betulin (1) has been subjected to a series of structural modifications for the purpose of evaluating resultant cancer cell growth inhibitory activity. The reaction sequence 7 → 11 → 12 was especially noteworthy in providing a betulin-derived amine dimer....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society and American Society of Pharmacognosy
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010298/ https://www.ncbi.nlm.nih.gov/pubmed/24694263 http://dx.doi.org/10.1021/np400947d |