A Phase I Clinical Trial of Systemically Delivered NEMO Binding Domain Peptide in Dogs with Spontaneous Activated B-Cell like Diffuse Large B-Cell Lymphoma

Activated B-Cell (ABC) Diffuse Large B-Cell Lymphoma (DLBCL) is a common, aggressive and poorly chemoresponsive subtype of DLBCL, characterized by constitutive canonical NF-κB signaling. Inhibition of NF-κB signaling leads to apoptosis of ABC-DLBCL cell lines, suggesting targeted disruption of this...

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Detalles Bibliográficos
Autores principales: Habineza Ndikuyeze, Georges, Gaurnier-Hausser, Anita, Patel, Reema, Baldwin, Albert S., May, Michael J., Flood, Patrick, Krick, Erika, Propert, Kathleen J., Mason, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010398/
https://www.ncbi.nlm.nih.gov/pubmed/24798348
http://dx.doi.org/10.1371/journal.pone.0095404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010398/
https://www.ncbi.nlm.nih.gov/pubmed/24798348
http://dx.doi.org/10.1371/journal.pone.0095404

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