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A Phase I Clinical Trial of Systemically Delivered NEMO Binding Domain Peptide in Dogs with Spontaneous Activated B-Cell like Diffuse Large B-Cell Lymphoma

Activated B-Cell (ABC) Diffuse Large B-Cell Lymphoma (DLBCL) is a common, aggressive and poorly chemoresponsive subtype of DLBCL, characterized by constitutive canonical NF-κB signaling. Inhibition of NF-κB signaling leads to apoptosis of ABC-DLBCL cell lines, suggesting targeted disruption of this...

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Detalles Bibliográficos
Autores principales:	Habineza Ndikuyeze, Georges, Gaurnier-Hausser, Anita, Patel, Reema, Baldwin, Albert S., May, Michael J., Flood, Patrick, Krick, Erika, Propert, Kathleen J., Mason, Nicola J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010398/ https://www.ncbi.nlm.nih.gov/pubmed/24798348 http://dx.doi.org/10.1371/journal.pone.0095404

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