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In Silico Prediction of Mutant HIV-1 Proteases Cleaving a Target Sequence

HIV-1 protease represents an appealing system for directed enzyme re-design, since it has various different endogenous targets, a relatively simple structure and it is well studied. Recently Chaudhury and Gray (Structure (2009) 17: 1636–1648) published a computational algorithm to discern the specif...

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Detalles Bibliográficos
Autores principales: Jensen, Jan H., Willemoës, Martin, Winther, Jakob R., De Vico, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010418/
https://www.ncbi.nlm.nih.gov/pubmed/24796579
http://dx.doi.org/10.1371/journal.pone.0095833