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In Silico Prediction of Mutant HIV-1 Proteases Cleaving a Target Sequence
HIV-1 protease represents an appealing system for directed enzyme re-design, since it has various different endogenous targets, a relatively simple structure and it is well studied. Recently Chaudhury and Gray (Structure (2009) 17: 1636–1648) published a computational algorithm to discern the specif...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010418/ https://www.ncbi.nlm.nih.gov/pubmed/24796579 http://dx.doi.org/10.1371/journal.pone.0095833 |