Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor

The nuclear receptors and xenosensors constitutive androstane receptor (CAR, NR1I3) and pregnane X receptor (PXR, NR1I2) induce the expression of xenobiotic metabolizing enzymes and transporters, which also affects various endobiotics. While human and mouse CAR feature a high basal activity and low...

Descripción completa

Detalles Bibliográficos
Autores principales: Mathäs, Marianne, Burk, Oliver, Gödtel-Armbrust, Ute, Herlyn, Holger, Wojnowski, Leszek, Windshügel, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010427/
https://www.ncbi.nlm.nih.gov/pubmed/24797902
http://dx.doi.org/10.1371/journal.pone.0096263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010427/
https://www.ncbi.nlm.nih.gov/pubmed/24797902
http://dx.doi.org/10.1371/journal.pone.0096263

Ejemplares similares