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NPM1 Silencing Reduces Tumour Growth and MAPK Signalling in Prostate Cancer Cells

The chaperone nucleophosmin (NPM1) is over-expressed in the epithelial compartment of prostate tumours compared to adjacent healthy epithelium and may represent one of the key actors that support the neoplastic phenotype of prostate adenocarcinoma cells. Yet, the mechanisms that underlie NPM1 mediat...

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Detalles Bibliográficos
Autores principales: Loubeau, Gaëlle, Boudra, Rafik, Maquaire, Sabrina, Lours-Calet, Corinne, Beaudoin, Claude, Verrelle, Pierre, Morel, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010470/
https://www.ncbi.nlm.nih.gov/pubmed/24796332
http://dx.doi.org/10.1371/journal.pone.0096293