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Pharmacokinetics and Efficacy of Topically Applied Nonsteroidal Anti-Inflammatory Drugs in Retinochoroidal Tissues in Rabbits

PURPOSE: To evaluate the pharmacokinetics and efficacy of topically applied nonsteroidal anti-inflammatory drugs (NSAIDs) in the retinochoroidal tissues of rabbits. METHODS: The cyclooxygenase (COX) inhibitory activity of diclofenac, bromfenac, and amfenac, an active metabolite of nepafenac, were de...

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Detalles Bibliográficos
Autores principales: Kida, Tetsuo, Kozai, Seiko, Takahashi, Hiroaki, Isaka, Mitsuyoshi, Tokushige, Hideki, Sakamoto, Taiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010472/
https://www.ncbi.nlm.nih.gov/pubmed/24796327
http://dx.doi.org/10.1371/journal.pone.0096481