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CaMKII Binding to GluN2B Is Differentially Affected by Macromolecular Crowding Reagents

Binding of the Ca(2+)/calmodulin(CaM)-dependent protein kinase II (CaMKII) to the NMDA-type glutamate receptor (NMDAR) subunit GluN2B controls long-term potentiation (LTP), a form of synaptic plasticity thought to underlie learning and memory. Regulation of this interaction is well-studied biochemic...

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Detalles Bibliográficos
Autores principales: Goodell, Dayton J., Eliseeva, Tatiana A., Coultrap, Steven J., Bayer, K. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010494/
https://www.ncbi.nlm.nih.gov/pubmed/24796865
http://dx.doi.org/10.1371/journal.pone.0096522