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Synthesis and Evaluation of Fluorine-Substituted Phenyl Acetate Derivatives as Ultra-Short Recovery Sedative/Hypnotic Agents

BACKGROUND: Soft drugs are molecules that are purposefully designed to be rapidly metabolized (metabolically labile). In anesthesia, the soft drug is useful because it enables precise titration to effect and rapid recovery, which might allow swift and clear-headed recovery of consciousness and early...

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Detalles Bibliográficos
Autores principales: Zhang, Heng, Xu, Xiangqing, Chen, Yin, Qiu, Yinli, Liu, Xin, Liu, Bi-Feng, Zhang, Guisen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010497/
https://www.ncbi.nlm.nih.gov/pubmed/24796695
http://dx.doi.org/10.1371/journal.pone.0096518