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IFN-γ Stimulates Autophagy-Mediated Clearance of Burkholderia cenocepacia in Human Cystic Fibrosis Macrophages

Burkholderia cenocepacia is a virulent pathogen that causes significant morbidity and mortality in patients with cystic fibrosis (CF), survives intracellularly in macrophages, and uniquely causes systemic infections in CF. Autophagy is a physiologic process that involves engulfing non-functional org...

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Detalles Bibliográficos
Autores principales: Assani, Kaivon, Tazi, Mia F., Amer, Amal O., Kopp, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010498/
https://www.ncbi.nlm.nih.gov/pubmed/24798083
http://dx.doi.org/10.1371/journal.pone.0096681