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Sensitivity and Specificity of In situ Proximity Ligation for Protein Interaction Analysis in a Model of Steatohepatitis with Mallory-Denk Bodies

The in situ proximity ligation assay (isPLA) is an increasingly used technology for in situ detection of protein interactions, post-translational modifications, and spatial relationships of antigens in cells and tissues, in general. In order to test its performance we compared isPLA with immunofluor...

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Detalles Bibliográficos
Autores principales: Zatloukal, Bernhard, Kufferath, Iris, Thueringer, Andrea, Landegren, Ulf, Zatloukal, Kurt, Haybaeck, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010503/
https://www.ncbi.nlm.nih.gov/pubmed/24798445
http://dx.doi.org/10.1371/journal.pone.0096690