Comparison between Karyotyping-FISH-Reverse Transcription PCR and RNA- Sequencing-Fusion Gene Identification Programs in the Detection of KAT6A-CREBBP in Acute Myeloid Leukemia

An acute myeloid leukemia was suspected of having a t(8;16)(p11;p13) resulting in a KAT6A-CREBBP fusion because the bone marrow was packed with monoblasts showing marked erythrophagocytosis. The diagnostic karyotype was 46,XY,add(1)(p13),t(8;21)(p11;q22),der(16)t(1;16)(p13;p13)[9]/46,XY[1]; thus, no...

Descripción completa

Detalles Bibliográficos
Autores principales: Panagopoulos, Ioannis, Torkildsen, Synne, Gorunova, Ludmila, Tierens, Anne, Tjønnfjord, Geir E., Heim, Sverre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010518/
https://www.ncbi.nlm.nih.gov/pubmed/24798186
http://dx.doi.org/10.1371/journal.pone.0096570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010518/
https://www.ncbi.nlm.nih.gov/pubmed/24798186
http://dx.doi.org/10.1371/journal.pone.0096570

Ejemplares similares