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Enhancement of the HIF-1α/15-LO/15-HETE Axis Promotes Hypoxia-Induced Endothelial Proliferation in Preeclamptic Pregnancy

Preeclampsia (PE) is an extremely serious condition in pregnant women and the leading cause of maternal and fetal morbidity and mortality. Despite active research, the etiological factors of this disorder remain elusive. The increased release of 15-hydroxyeicosatetraenoic acid (15-HETE) in the place...

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Detalles Bibliográficos
Autores principales: Yuan, Dandan, Ran, Yajuan, Liu, Qian, Zhang, Yanhua, Li, Huiying, Li, Peiling, Zhu, Daling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010521/
https://www.ncbi.nlm.nih.gov/pubmed/24796548
http://dx.doi.org/10.1371/journal.pone.0096510