A Novel Antibody against Human Properdin Inhibits the Alternative Complement System and Specifically Detects Properdin from Blood Samples

The complement system is an essential part of the innate immune system by acting as a first line of defense which is stabilized by properdin, the sole known positive regulator of the alternative complement pathway. Dysregulation of complement can promote a diversity of human inflammatory diseases wh...

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Detalles Bibliográficos
Autores principales: Pauly, Diana, Nagel, Benedikt M., Reinders, Jörg, Killian, Tobias, Wulf, Matthias, Ackermann, Susanne, Ehrenstein, Boris, Zipfel, Peter F., Skerka, Christine, Weber, Bernhard H. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010523/
https://www.ncbi.nlm.nih.gov/pubmed/24797388
http://dx.doi.org/10.1371/journal.pone.0096371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010523/
https://www.ncbi.nlm.nih.gov/pubmed/24797388
http://dx.doi.org/10.1371/journal.pone.0096371

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