Cargando…

A New Genetically Encoded Single-Chain Biosensor for Cdc42 Based on FRET, Useful for Live-Cell Imaging

Cdc42 is critical in a myriad of cellular morphogenic processes, requiring precisely regulated activation dynamics to affect specific cellular events. To facilitate direct observations of Cdc42 activation in live cells, we developed and validated a new biosensor of Cdc42 activation. The biosensor is...

Descripción completa

Detalles Bibliográficos
Autores principales: Hanna, Samer, Miskolci, Veronika, Cox, Dianne, Hodgson, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010534/
https://www.ncbi.nlm.nih.gov/pubmed/24798463
http://dx.doi.org/10.1371/journal.pone.0096469