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A New Genetically Encoded Single-Chain Biosensor for Cdc42 Based on FRET, Useful for Live-Cell Imaging
Cdc42 is critical in a myriad of cellular morphogenic processes, requiring precisely regulated activation dynamics to affect specific cellular events. To facilitate direct observations of Cdc42 activation in live cells, we developed and validated a new biosensor of Cdc42 activation. The biosensor is...
Autores principales: | Hanna, Samer, Miskolci, Veronika, Cox, Dianne, Hodgson, Louis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010534/ https://www.ncbi.nlm.nih.gov/pubmed/24798463 http://dx.doi.org/10.1371/journal.pone.0096469 |
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