Formulation development for the orexin receptor antagonist almorexant: assessment in two clinical studies

Almorexant, a dual orexin receptor antagonist, was investigated for the treatment of insomnia. The following observations initiated further formulation development: the active pharmaceutical ingredient (API) was sticking to the apparatus used during tablet compression; almorexant has an absolute bio...

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Detalles Bibliográficos
Autores principales: Dingemanse, Jasper, Gehin, Martine, Cruz, Hans Gabriel, Hoever, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010641/
https://www.ncbi.nlm.nih.gov/pubmed/24812492
http://dx.doi.org/10.2147/DDDT.S62118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010641/
https://www.ncbi.nlm.nih.gov/pubmed/24812492
http://dx.doi.org/10.2147/DDDT.S62118

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