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Dissection of a Ciona regulatory element reveals complexity of cross-species enhancer activity

Vertebrate genomes share numerous conserved non-coding elements, many of which function as enhancer elements and are hypothesised to be under evolutionary constraint due to a need to be bound by combinations of sequence-specific transcription factors. In contrast, few such conserved elements can be...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Chung, Pauls, Stefan, Bacha, Jamil, Elgar, Greg, Loose, Matthew, Shimeld, Sebastian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010673/
https://www.ncbi.nlm.nih.gov/pubmed/24680932
http://dx.doi.org/10.1016/j.ydbio.2014.03.013