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Acromegaly Clinical Trial Methodology Impact on Reported Biochemical Efficacy Rates of Somatostatin Receptor Ligand Treatments: A Meta-Analysis

INTRODUCTION: Biochemical efficacy of somatostatin receptor ligand (SRL) treatment in acromegaly is defined by metrics for GH and IGF-1 control. Since the earliest therapeutic trials, biochemical control criteria, medical formulations, and assay techniques have evolved. MATERIALS AND METHODS: We sea...

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Detalles Bibliográficos
Autores principales: Carmichael, John D., Bonert, Vivien S., Nuño, Miriam, Ly, Diana, Melmed, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010703/
https://www.ncbi.nlm.nih.gov/pubmed/24606084
http://dx.doi.org/10.1210/jc.2013-3757