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The iFat1 transgene permits conditional endogenous n-3 PUFA enrichment both in vitro and in vivo

Fat-1 transgenic mice, which endogenously convert n-6 PUFA to n-3 PUFA, are a useful tool in health research; however with this model timing of n-3 PUFA enrichment cannot be directly controlled. To add such capability, the novel Cre-recombinase inducible fat-1 (iFat1) transgenic mouse has been devel...

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Detalles Bibliográficos
Autores principales: Clarke, Shannon E., Kang, Jing X., Ma, David W. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010720/
https://www.ncbi.nlm.nih.gov/pubmed/24622775
http://dx.doi.org/10.1007/s11248-014-9788-x