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An approach for exploring interaction between two proteins in vivo

We describe a strategy for exploring the function of protein-protein interactions in striated muscle in vivo. We describe our experience using this strategy to study the interaction of UNC-112 (kindlin) with PAT-4 (integrin linked kinase). Random mutagenesis is used to generate a collection of mutan...

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Detalles Bibliográficos
Autores principales: Qadota, Hiroshi, Benian, Guy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010775/
https://www.ncbi.nlm.nih.gov/pubmed/24808865
http://dx.doi.org/10.3389/fphys.2014.00162