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Correlation of measured and calculated serum osmolality during mannitol or hypertonic saline infusion in patients after craniotomy: a study protocol and statistical analysis plan for a randomised controlled trial

INTRODUCTION: Brain oedema is a major complication after craniotomy. Hyperosmolar agents have been used as the medical treatment for this condition. Measurement and estimation of serum osmolality during hyperosmolar agent infusion is of clinical importance to evaluate clinical efficacy, adjust dosag...

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Detalles Bibliográficos
Autores principales: Li, Qian, Xu, Ming, Zhou, Jian-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010815/
https://www.ncbi.nlm.nih.gov/pubmed/24760352
http://dx.doi.org/10.1136/bmjopen-2014-004921