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Targeting CXCR7/ACKR3 as a therapeutic strategy to promote remyelination in the adult central nervous system

Current treatment modalities for the neurodegenerative disease multiple sclerosis (MS) use disease-modifying immunosuppressive compounds but do not promote repair. Although several potential targets that may induce myelin production have been identified, there has yet to be an approved therapy that...

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Detalles Bibliográficos
Autores principales: Williams, Jessica L., Patel, Jigisha R., Daniels, Brian P., Klein, Robyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010893/
https://www.ncbi.nlm.nih.gov/pubmed/24733828
http://dx.doi.org/10.1084/jem.20131224