Cargando…

Targeting CXCR7/ACKR3 as a therapeutic strategy to promote remyelination in the adult central nervous system

Current treatment modalities for the neurodegenerative disease multiple sclerosis (MS) use disease-modifying immunosuppressive compounds but do not promote repair. Although several potential targets that may induce myelin production have been identified, there has yet to be an approved therapy that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Williams, Jessica L., Patel, Jigisha R., Daniels, Brian P., Klein, Robyn S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010893/ https://www.ncbi.nlm.nih.gov/pubmed/24733828 http://dx.doi.org/10.1084/jem.20131224

Ejemplares similares

ACKR4 restrains antitumor immunity by regulating CCL21
por: Whyte, Carly E., et al.
Publicado: (2020)

Central Nervous System Pathology Progresses Independently of KC and CXCR2 in Globoid-Cell Leukodystrophy
por: Reddy, Adarsh S., et al.
Publicado: (2013)

TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination
por: Gouna, Garyfallia, et al.
Publicado: (2021)

Cooperating Mechanisms of CXCR5 and CCR7 in Development and Organization of Secondary Lymphoid Organs
por: Ohl, Lars, et al.
Publicado: (2003)

Atypical Roles of the Chemokine Receptor ACKR3/CXCR7 in Platelet Pathophysiology
por: Chatterjee, Madhumita
Publicado: (2022)

LATENT HERPES SIMPLEX VIRUS IN THE CENTRAL NERVOUS SYSTEM OF RABBITS AND MICE
por: Knotts, F. B., et al.
Publicado: (1973)

Chlamydia pneumoniae Infection of the Central Nervous System Worsens Experimental Allergic Encephalitis
por: Du, Caigan, et al.
Publicado: (2002)

CXCR4 is required for the quiescence of primitive hematopoietic cells
por: Nie, Yuchun, et al.
Publicado: (2008)

BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
por: Krumbholz, Markus, et al.
Publicado: (2005)

Requirement of the Chemokine Receptor CXCR3 for Acute Allograft Rejection
por: Hancock, Wayne W., et al.
Publicado: (2000)

Critical Points of Tumor Necrosis Factor Action in Central Nervous System Autoimmune Inflammation Defined by Gene Targeting
por: Körner, Heinrich, et al.
Publicado: (1997)

CXCR4 promotes B cell egress from Peyer’s patches
por: Schmidt, Timothy H., et al.
Publicado: (2013)

The natural analgesic conolidine targets the newly identified opioid scavenger ACKR3/CXCR7
por: Szpakowska, Martyna, et al.
Publicado: (2021)

Peroxisome proliferator–activated receptor δ limits the expansion of pathogenic Th cells during central nervous system autoimmunity
por: Dunn, Shannon E., et al.
Publicado: (2010)

CXCR2- and E-Selectin–induced Neutrophil Arrest during Inflammation In Vivo
por: Smith, Michael L., et al.
Publicado: (2004)

Inhibition of T-tropic HIV Strains by Selective Antagonization of the Chemokine Receptor CXCR4
por: Schols, Dominique, et al.
Publicado: (1997)

IFN-γ– and IL-10–expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis
por: Zhao, Jingxian, et al.
Publicado: (2011)

The choline pathway as a strategy to promote central nervous system (CNS) remyelination
por: Skripuletz, Thomas, et al.
Publicado: (2015)

Emerging Cellular and Molecular Strategies for Enhancing Central Nervous System (CNS) Remyelination
por: Abu-Rub, Mohammad, et al.
Publicado: (2018)

CXCR4/fusin Is Not a Species-specific Barrier in Murine Cells for HIV-1 Entry
por: Tachibana, Kazunobu, et al.
Publicado: (1997)

Bone Marrow–generated Dendritic Cells Pulsed with Tumor Extracts or Tumor RNA Induce Antitumor Immunity against Central Nervous System Tumors
por: Ashley, David M., et al.
Publicado: (1997)

The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides
por: Meyrath, Max, et al.
Publicado: (2020)

Signal Transduction Due to HIV-1 Envelope Interactions with Chemokine Receptors CXCR4 or CCR5
por: Davis, Craig B., et al.
Publicado: (1997)

A Small Molecule CXCR4 Inhibitor that Blocks T Cell Line–tropic HIV-1 Infection
por: Murakami, Tsutomu, et al.
Publicado: (1997)

Type I IFN suppresses Cxcr2 driven neutrophil recruitment into the sensory ganglia during viral infection
por: Stock, Angus T., et al.
Publicado: (2014)

Phospholipase D2 drives mortality in sepsis by inhibiting neutrophil extracellular trap formation and down-regulating CXCR2
por: Lee, Sung Kyun, et al.
Publicado: (2015)

The Role of the CXCL12/CXCR4/ACKR3 Axis in Autoimmune Diseases
por: García-Cuesta, Eva M., et al.
Publicado: (2019)

Human Nerve Growth Factor Protects Common Marmosets against Autoimmune Encephalomyelitis by Switching the Balance of T Helper Cell Type 1 and 2 Cytokines within the Central Nervous System
por: Villoslada, Pablo, et al.
Publicado: (2000)

Proadrenomedullin N-Terminal 20 Peptides (PAMPs) Are Agonists of the Chemokine Scavenger Receptor ACKR3/CXCR7
por: Meyrath, Max, et al.
Publicado: (2021)

The Polarity Protein Scribble Regulates Myelination and Remyelination in the Central Nervous System
por: Jarjour, Andrew A., et al.
Publicado: (2015)

A Small-molecule Inhibitor Directed against the Chemokine Receptor CXCR4 Prevents its Use as an HIV-1 Coreceptor
por: Doranz, Benjamin J., et al.
Publicado: (1997)

The contribution of oligodendrocytes and oligodendrocyte progenitor cells to central nervous system repair in multiple sclerosis: perspectives for remyelination therapeutic strategies
por: Dulamea, Adriana Octaviana
Publicado: (2017)

Central nervous system remyelination in culture — A tool for multiple sclerosis research
por: Zhang, Hui, et al.
Publicado: (2011)

Leptin sustains spontaneous remyelination in the adult central nervous system
por: Matoba, Ken, et al.
Publicado: (2017)

Crosstalk between CXCR4/ACKR3 and EGFR Signaling in Breast Cancer Cells
por: Neves, Maria, et al.
Publicado: (2022)

B Cell–attracting Chemokine 1, a Human CXC Chemokine Expressed in Lymphoid Tissues, Selectively Attracts B Lymphocytes via BLR1/CXCR5
por: Legler, Daniel F., et al.
Publicado: (1998)

Chemokines Referee Inflammation within the Central Nervous System during Infection and Disease
por: Durrant, Douglas M., et al.
Publicado: (2014)

Resistance to Experimental Autoimmune Encephalomyelitis in Mice Lacking the Cc Chemokine Receptor (Ccr2)
por: Izikson, Leonid, et al.
Publicado: (2000)

Resistance of CD7-deficient Mice to Lipopolysaccharide-induced Shock Syndromes
por: Sempowski, Gregory D., et al.
Publicado: (1999)

From fish to man: understanding endogenous remyelination in central nervous system demyelinating diseases
por: Dubois-Dalcq, Monique, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_3b7tkg80snct3so6g44m0sn9ad