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B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS

Activation of intrinsic growth programs that promote developmental axon growth may also facilitate axon regeneration in injured adult neurons. Here, we demonstrate that conditional activation of B-RAF kinase alone in mouse embryonic neurons is sufficient to drive the growth of long-range peripheral...

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Detalles Bibliográficos
Autores principales: O’Donovan, Kevin J., Ma, Kaijie, Guo, Hengchang, Wang, Chen, Sun, Fang, Han, Seung Baek, Kim, Hyukmin, Wong, Jamie K., Charron, Jean, Zou, Hongyan, Son, Young-Jin, He, Zhigang, Zhong, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010899/
https://www.ncbi.nlm.nih.gov/pubmed/24733831
http://dx.doi.org/10.1084/jem.20131780