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B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS
Activation of intrinsic growth programs that promote developmental axon growth may also facilitate axon regeneration in injured adult neurons. Here, we demonstrate that conditional activation of B-RAF kinase alone in mouse embryonic neurons is sufficient to drive the growth of long-range peripheral...
Autores principales: | O’Donovan, Kevin J., Ma, Kaijie, Guo, Hengchang, Wang, Chen, Sun, Fang, Han, Seung Baek, Kim, Hyukmin, Wong, Jamie K., Charron, Jean, Zou, Hongyan, Son, Young-Jin, He, Zhigang, Zhong, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010899/ https://www.ncbi.nlm.nih.gov/pubmed/24733831 http://dx.doi.org/10.1084/jem.20131780 |
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