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Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection
Regulatory T (T reg) cells play an essential role in preventing autoimmunity but can also impair clearance of foreign pathogens. Paradoxically, signals known to promote T reg cell function are abundant during infection and could inappropriately enhance T reg cell activity. How T reg cell function is...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010906/ https://www.ncbi.nlm.nih.gov/pubmed/24711580 http://dx.doi.org/10.1084/jem.20131556 |