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Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection

Regulatory T (T reg) cells play an essential role in preventing autoimmunity but can also impair clearance of foreign pathogens. Paradoxically, signals known to promote T reg cell function are abundant during infection and could inappropriately enhance T reg cell activity. How T reg cell function is...

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Detalles Bibliográficos
Autores principales:	Srivastava, Shivani, Koch, Meghan A., Pepper, Marion, Campbell, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010906/ https://www.ncbi.nlm.nih.gov/pubmed/24711580 http://dx.doi.org/10.1084/jem.20131556

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