Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation

The zinc finger transcriptional repressor Gfi-1b is essential for erythroid and megakaryocytic development in the embryo. Its roles in the maintenance of bone marrow erythropoiesis and thrombopoiesis have not been defined. We investigated Gfi-1b’s adult functions using a loxP-flanked Gfi-1b allele i...

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Detalles Bibliográficos
Autores principales: Foudi, Adlen, Kramer, Daniel J., Qin, Jinzhong, Ye, Denise, Behlich, Anna-Sophie, Mordecai, Scott, Preffer, Frederic I., Amzallag, Arnaud, Ramaswamy, Sridhar, Hochedlinger, Konrad, Orkin, Stuart H., Hock, Hanno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010908/
https://www.ncbi.nlm.nih.gov/pubmed/24711581
http://dx.doi.org/10.1084/jem.20131065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010908/
https://www.ncbi.nlm.nih.gov/pubmed/24711581
http://dx.doi.org/10.1084/jem.20131065

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