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Assembly and Validation of Versatile Transcription Activator-Like Effector Libraries

The ability to perturb individual genes in genome-wide experiments has been instrumental in unraveling cellular and disease properties. Here we introduce, describe the assembly, and demonstrate the use of comprehensive and versatile transcription activator-like effector (TALE) libraries. As a proof...

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Detalles Bibliográficos
Autores principales: Li, Yi, Ehrhardt, Kristina, Zhang, Michael Q., Bleris, Leonidas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010924/
https://www.ncbi.nlm.nih.gov/pubmed/24798576
http://dx.doi.org/10.1038/srep04857