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de novo Synthesis of a Bacterial Toxin/Antitoxin System
The prevalence of toxin/antitoxin (TA) systems in almost all genomes suggests they evolve rapidly. Here we show that an antitoxin from a type V system (GhoS, an endoribonuclease specific for the mRNA of the toxin GhoT) can be converted into a novel toxin (ArT) simply by adding two mutations. In cont...
Autores principales: | Soo, Valerie W. C., Cheng, Hsin-Yao, Kwan, Brian W., Wood, Thomas K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010927/ https://www.ncbi.nlm.nih.gov/pubmed/24797297 http://dx.doi.org/10.1038/srep04807 |
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