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Nap1 stimulates homologous recombination by RAD51 and RAD54 in higher-ordered chromatin containing histone H1

Homologous recombination plays essential roles in mitotic DNA double strand break (DSB) repair and meiotic genetic recombination. In eukaryotes, RAD51 promotes the central homologous-pairing step during homologous recombination, but is not sufficient to overcome the reaction barrier imposed by nucle...

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Detalles Bibliográficos
Autores principales: Machida, Shinichi, Takaku, Motoki, Ikura, Masae, Sun, Jiying, Suzuki, Hidekazu, Kobayashi, Wataru, Kinomura, Aiko, Osakabe, Akihisa, Tachiwana, Hiroaki, Horikoshi, Yasunori, Fukuto, Atsuhiko, Matsuda, Ryo, Ura, Kiyoe, Tashiro, Satoshi, Ikura, Tsuyoshi, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010968/
https://www.ncbi.nlm.nih.gov/pubmed/24798879
http://dx.doi.org/10.1038/srep04863