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Small Interfering RNA Targeting Nerve Growth Factor Alleviates Allergic Airway Hyperresponsiveness

Airway hyperresponsiveness is the hallmark of allergic asthma and caused by multiple factors. Nerve growth factor (NGF), a neurotrophin, is originally known for regulation of neural circuit development and function. Recent studies indicated that NGF contributes to airway hyperresponsiveness and path...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Lien, Huang, Hsin-Ying, Lee, Chen-Chen, Chiang, Bor-Luen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011123/
https://www.ncbi.nlm.nih.gov/pubmed/24714423
http://dx.doi.org/10.1038/mtna.2014.11