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Filament formation by metabolic enzymes is a specific adaptation to an advanced state of cellular starvation

One of the key questions in biology is how the metabolism of a cell responds to changes in the environment. In budding yeast, starvation causes a drop in intracellular pH, but the functional role of this pH change is not well understood. Here, we show that the enzyme glutamine synthetase (Gln1) form...

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Detalles Bibliográficos
Autores principales: Petrovska, Ivana, Nüske, Elisabeth, Munder, Matthias C, Kulasegaran, Gayathrie, Malinovska, Liliana, Kroschwald, Sonja, Richter, Doris, Fahmy, Karim, Gibson, Kimberley, Verbavatz, Jean-Marc, Alberti, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011332/
https://www.ncbi.nlm.nih.gov/pubmed/24771766
http://dx.doi.org/10.7554/eLife.02409