Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability

Ribosomal proteins (RPs) have gained much attention for their extraribosomal functions particularly with respect to p53 regulation. To date, about fourteen RPs have shown to bind to MDM2 and regulate p53. Upon binding to MDM2, the RPs suppress MDM2 E3 ubiquitin ligase activity resulting in the stabi...

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Detalles Bibliográficos
Autores principales: Kim, Tae-Hyung, Leslie, Patrick, Zhang, Yanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011588/
https://www.ncbi.nlm.nih.gov/pubmed/24658219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011588/
https://www.ncbi.nlm.nih.gov/pubmed/24658219

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