Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer

Epithelial ovarian cancer is a highly lethal and aggressive gynecological malignancy. The high mortality rate is due in part to the fact that many advanced cancer patients become refractory to current chemotherapeutic agents, leading to tumor recurrence and death. However, the underlying mechanisms...

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Detalles Bibliográficos
Autores principales: Liu, Michelle X., Siu, Michelle KY., Liu, Stephanie S., Yam, Judy WP., Ngan, Hextan YS., Chan, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011596/
https://www.ncbi.nlm.nih.gov/pubmed/24659709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011596/
https://www.ncbi.nlm.nih.gov/pubmed/24659709

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