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The Kinematics of Cytotoxic Lymphocytes Influence Their Ability to Kill Target Cells

Cytotoxic lymphocytes (CTL) have been reported to show a range of motility patterns from rapid long-range tracking to complete arrest, but how and whether these kinematics affect their ability to kill target cells is not known. Many in vitro killing assays utilize cell lines and tumour-derived cells...

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Detalles Bibliográficos
Autores principales: Bhat, Purnima, Leggatt, Graham, Matthaei, Klaus I., Frazer, Ian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011687/
https://www.ncbi.nlm.nih.gov/pubmed/24801876
http://dx.doi.org/10.1371/journal.pone.0095248