Yeast Frataxin Is Stabilized by Low Salt Concentrations: Cold Denaturation Disentangles Ionic Strength Effects from Specific Interactions

Frataxins are a family of metal binding proteins associated with the human Friedreich's ataxia disease. Here, we have addressed the effect of non-specifically binding salts on the stability of the yeast ortholog Yfh1. This protein is a sensitive model since its stability is strongly dependent o...

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Detalles Bibliográficos
Autores principales: Sanfelice, Domenico, Puglisi, Rita, Martin, Stephen R., Di Bari, Lorenzo, Pastore, Annalisa, Temussi, Piero Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011691/
https://www.ncbi.nlm.nih.gov/pubmed/24802807
http://dx.doi.org/10.1371/journal.pone.0095801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011691/
https://www.ncbi.nlm.nih.gov/pubmed/24802807
http://dx.doi.org/10.1371/journal.pone.0095801

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