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Lac Repressor Mediated DNA Looping: Monte Carlo Simulation of Constrained DNA Molecules Complemented with Current Experimental Results

Tethered particle motion (TPM) experiments can be used to detect time-resolved loop formation in a single DNA molecule by measuring changes in the length of a DNA tether. Interpretation of such experiments is greatly aided by computer simulations of DNA looping which allow one to analyze the structu...

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Detalles Bibliográficos
Autores principales: Biton, Yoav Y., Kumar, Sandip, Dunlap, David, Swigon, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011716/
https://www.ncbi.nlm.nih.gov/pubmed/24800809
http://dx.doi.org/10.1371/journal.pone.0092475