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Immunosuppressive Activity of Daphnetin, One of Coumarin Derivatives, Is Mediated through Suppression of NF-κB and NFAT Signaling Pathways in Mouse T Cells

Daphnetin, a plant-derived dihydroxylated derivative of coumarin, is an effective compound extracted from a plant called Daphne Korean Nakai. Coumarin derivates were known for their antithrombotic, anti-inflammatory, and antioxidant activities. The present study was aimed to determine the immunosupp...

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Detalles Bibliográficos
Autores principales: Song, Bocui, Wang, Zhenning, Liu, Yan, Xu, Sisi, Huang, Guoren, Xiong, Ying, Zhang, Shuang, Xu, Linli, Deng, Xuming, Guan, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011761/
https://www.ncbi.nlm.nih.gov/pubmed/24800925
http://dx.doi.org/10.1371/journal.pone.0096502