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Haploinsufficiency of Def Activates p53-Dependent TGFβ Signalling and Causes Scar Formation after Partial Hepatectomy

The metazoan liver exhibits a remarkable capacity to regenerate lost liver mass without leaving a scar following partial hepatectomy (PH). Whilst previous studies have identified components of several different signaling pathways that are essential for activation of hepatocyte proliferation during l...

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Detalles Bibliográficos
Autores principales: Zhu, Zhihui, Chen, Jun, Xiong, Jing-Wei, Peng, Jinrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011785/
https://www.ncbi.nlm.nih.gov/pubmed/24801718
http://dx.doi.org/10.1371/journal.pone.0096576