Efficacy and Side Effects of Natalizumab Therapy in Patients with Multiple Sclerosis

Natalizumab (Nat) is a humanized monoclonal antibody used for the treatment of relapsing multiple sclerosis (MS). Nat inhibits lymphocyte migration via the blood brain barrier (BBB) by blockage of an integrin adhesion molecule, very late antigen 4. During the phase III clinical trials, it was shown...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoepner, Robert, Faissner, Simon, Salmen, Anke, Gold, Ralf, Chan, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011812/
https://www.ncbi.nlm.nih.gov/pubmed/24855407
http://dx.doi.org/10.4137/JCNSD.S14049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011812/
https://www.ncbi.nlm.nih.gov/pubmed/24855407
http://dx.doi.org/10.4137/JCNSD.S14049

Ejemplares similares