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Anti-PD-1 antibodies for the treatment of B-cell lymphoma: Importance of PD-1(+) T-cell subsets

Monoclonal antibodies specific for programmed cell death 1 (PDCD1, best known as PD-1) have been shown to mediate antineoplastic effects in follicular lymphoma patients. However, the relative proportion of intratumoral PD-1(+) T-cell subsets, in particular follicular helper T cells (which exert pro-...

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Detalles Bibliográficos
Autores principales: Chu, Fuliang, Neelapu, Sattva S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011813/
https://www.ncbi.nlm.nih.gov/pubmed/24808975
http://dx.doi.org/10.4161/onci.28101