Reduced Blood Pressure of CFTR-F508del Carriers Correlates with Diminished Arterial Reactivity Rather than Circulating Blood Volume in Mice

The F508del mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) is the most common cause of cystic fibrosis (CF). Both CF patients and F508del carriers have decreased blood pressure. While this has been attributed to salt depletion, recent studies have shown F508del expression...

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Detalles Bibliográficos
Autores principales: Peotta, Veronica A., Bhandary, Prasad, Ogu, Ugochi, Volk, Kenneth A., Roghair, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011854/
https://www.ncbi.nlm.nih.gov/pubmed/24801204
http://dx.doi.org/10.1371/journal.pone.0096756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011854/
https://www.ncbi.nlm.nih.gov/pubmed/24801204
http://dx.doi.org/10.1371/journal.pone.0096756

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