The Role of H1 Linker Histone Subtypes in Preserving the Fidelity of Elaboration of Mesendodermal and Neuroectodermal Lineages during Embryonic Development

H1 linker histone proteins are essential for the structural and functional integrity of chromatin and for the fidelity of additional epigenetic modifications. Deletion of H1c, H1d and H1e in mice leads to embryonic lethality by mid-gestation with a broad spectrum of developmental alterations. To elu...

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Detalles Bibliográficos
Autores principales: Nguyen, Giang D., Gokhan, Solen, Molero, Aldrin E., Yang, Seung-Min, Kim, Byung-Ju, Skoultchi, Arthur I., Mehler, Mark F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011883/
https://www.ncbi.nlm.nih.gov/pubmed/24802750
http://dx.doi.org/10.1371/journal.pone.0096858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011883/
https://www.ncbi.nlm.nih.gov/pubmed/24802750
http://dx.doi.org/10.1371/journal.pone.0096858

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