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Mechanisms Underlying Plk1 Polo-Box Domain-Mediated Biological Processes and Their Physiological Significance

Mammalian polo-like kinase 1 (Plk1) has been studied intensively as a key regulator of various cell cycle events that are critical for proper M-phase progression. The polo-box domain (PBD) present in Plk1’s C-terminal non-catalytic region has been shown to play a central role in targeting the N-term...

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Detalles Bibliográficos
Autores principales: Lee, Kyung S., Park, Jung-Eun, Kang, Young Hwi, Kim, Tae-Sung, Bang, Jeong K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012076/
https://www.ncbi.nlm.nih.gov/pubmed/24722413
http://dx.doi.org/10.14348/molcells.2014.0002