Disruption of the Myostatin Gene in Porcine Primary Fibroblasts and Embryos Using Zinc-Finger Nucleases

Myostatin represses muscle growth by negatively regulating the number and size of muscle fibers. Myostatin loss-of-function can result in the double-muscling phenotype and increased muscle mass. Thus, knockout of myostatin gene could improve the quality of meat from mammals. In the present study, zi...

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Detalles Bibliográficos
Autores principales: Huang, Xian-Ju, Zhang, Hong-Xiao, Wang, Huili, Xiong, Kai, Qin, Ling, Liu, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012078/
https://www.ncbi.nlm.nih.gov/pubmed/24802055
http://dx.doi.org/10.14348/molcells.2014.2209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012078/
https://www.ncbi.nlm.nih.gov/pubmed/24802055
http://dx.doi.org/10.14348/molcells.2014.2209

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