Effect of the Brugada syndrome mutation A39V on calmodulin regulation of Cav1.2 channels

BACKGROUND: The L-type calcium channel Cav1.2 is important for brain and heart function. The ubiquitous calcium sensing protein calmodulin (CaM) regulates calcium dependent gating of Cav1.2 channels by reducing calcium influx, a process known as calcium-dependent inactivation (CDI). Dissecting the c...

Descripción completa

Detalles Bibliográficos
Autores principales: Simms, Brett A, Souza, Ivana Assis, Zamponi, Gerald W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012176/
https://www.ncbi.nlm.nih.gov/pubmed/24775099
http://dx.doi.org/10.1186/1756-6606-7-34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012176/
https://www.ncbi.nlm.nih.gov/pubmed/24775099
http://dx.doi.org/10.1186/1756-6606-7-34

Ejemplares similares