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Mice with altered BDNF signaling as models for mood disorders and antidepressant effects

Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase TrkB support neuronal survival during development and promote connectivity and plasticity in the adult brain. Decreased BDNF signaling is associated with the pathophysiology of depression and the mechanisms underlying the acti...

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Detalles Bibliográficos
Autores principales: Lindholm, Jesse S. O., Castrén, Eero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012208/
https://www.ncbi.nlm.nih.gov/pubmed/24817844
http://dx.doi.org/10.3389/fnbeh.2014.00143