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Mice with altered BDNF signaling as models for mood disorders and antidepressant effects
Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase TrkB support neuronal survival during development and promote connectivity and plasticity in the adult brain. Decreased BDNF signaling is associated with the pathophysiology of depression and the mechanisms underlying the acti...
Autores principales: | Lindholm, Jesse S. O., Castrén, Eero |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012208/ https://www.ncbi.nlm.nih.gov/pubmed/24817844 http://dx.doi.org/10.3389/fnbeh.2014.00143 |
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